ISSN: 2048-9145

Pharmaceutical Bioprocessing

Articles Related To Drug Discovery

Drug discovery is the process through which potential new medicines are identified. It involves a wide range of scientific disciplines, including biology, chemistry and pharmacology. New drugs are continually required by the healthcare systems to address unmet medical needs across diverse therapeutic areas, and pharmaceutical industries primarily strive to deliver new drugs to the market through the complex activities of drug discovery and development. Discovery involves a number of processes like target identification and validation, hit identification, lead generation and optimization and finally the identification of a candidate for further development. Development, on the other hand, includes optimization of chemical synthesis and its formulation, toxicological studies in animals, clinical trials, and eventually regulatory approval. Both of these processes are time-consuming and expensive and currently the industry is under pressure owing to the extremely stringent regulatory requirements, environmental concerns, and reduced incomes due to patent expirations. These issues have had an adverse bearing on the R&D productivity in recent years, hence there is a need for innovative approaches as well as increased collaboration between industry, academia, and governmental research institutions, with a common objective of constantly delivering quality medicines.    

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