Articles Open Access In System Biology

 Since the target may be a model of the interactions in a very system, the experimental techniques that the majority suit systems biology area unit people who area unit system-wide and commit to be as complete as attainable. Therefore, transcriptomics, metabolomics, genetic science and high-throughput techniques area unit accustomed collect quantitative knowledge for the development and validation of models.According to the interpretation of Systems Biology because the ability to get, integrate and analyze complicated knowledge sets from multiple experimental sources victimisation knowledge domain tools, some typical technology platforms area unit phenomics, organismic variation in makeup because it changes throughout its life span; genetics, organismic polymer (DNA) sequence, as well as intra-organismal cell specific variation. (i.e., end length variation); epigenomics/epigenetics, organismic and corresponding cell specific transcriptomic control factors not by trial and error coded within the genomic sequence. (i.e., DNA methylation, simple protein acylation and deacetylation, etc.); transcriptomics, organismal, tissue or whole cell organic phenomenon measurements by DNA microarrays or serial analysis of sequence expression; interferomics, organismal, tissue, or cell-level transcript correcting factors (i.e., polymer interference), proteomics, organismal, tissue, or cell level measurements of proteins and peptides via two-dimensional gel cataphoresis, mass spectroscopy or multi-dimensional supermolecule identification techniques (advanced HPLC systems including mass spectrometry). Sub disciplines embrace phosphoproteomics, glycoproteomics and different ways to discover with chemicals changed proteins; metabolomics, measurements of tiny molecules referred to as metabolites within the system at the organismic, cell, or tissue level  glycomics, organismal, tissue, or cell-level measurements of carbohydrates; lipidomics, organismal, tissue, or cell level measurements of lipids.

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