Stem Cell Research and Regenerative Medicine

Antioxidants In Dentistry Scholarly Journal

 Oxygen is a component indispensable for all times, will act each therefore on promote and deteriorate heath of the body. The toxic effects of element were unknown till Gershman’s radical theory of element toxicity in 1954, that states that the toxicity of element is because of part reduced varieties of element . once cells use element to come up with energy within the kind of nucleotide within the mitochondria, free radicals square measure created. Free radicals square measure with chemicals active atoms that have a charge because of Associate in Nursing excess or deficient variety of electrons. they'll be reactive element species (ROS) or reactive gas species (RNS) . ROS and RNS square measure well recognized for enjoying a twin role as each injurious and helpful species. ROS square measure extremely reactive molecules derived from element metabolism. In vivo, a number of these ROS play constructive roles in cell physiology; but, they will conjointly cause nice destruction to cell membranes and polymer, by inflicting membrane supermolecule peroxidation, small membrane thinness, and polymer mutations resulting in cancer, chronic, and alternative diseases. ROS levels increase intensely and lead to vital injury to cell structures throughout aerophilous stress. ROS square measure cytotoxic and are involved within the aetiology of assorted human diseases. Thus, ROS will kill microorganism however it conjointly destroys the adjacent infected host tissues. ROS scavengers/ antioxidants square measure of prime importance for preventing and dominant human diseases by counteracting ROS formation. Antioxidants square measure useful in preventing the harmful effects of ROS by reacting with element.

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