Phytotoxins and mycotoxins created by parasitic plant pathogens are for the most part moo atomic weight auxiliary metabolites that apply harmful impacts on have plants and creatures, individually. Among the phytotoxins, host-specific poisons (HSTs) are basic determinants of pathogenicity or destructiveness in a few plantâ pathogen intelligent. The AAL-toxin and fumonisin are basically related and were initially disconnected from the tomato pathotype of Alternaria alternata (equivalent word A. alternata f. sp. lycopersici, equivalent word A. arborescens) and from Gibberella moniliformis, individually. These mycotoxins are moo atomic weight auxiliary metabolites with different chemical structures. All the HSTs have diverse mode of activities, biochemical responses, and signaling components to causes illnesses within the have plants. These HSTs have obliterating impacts on have plant tissues by influencing biochemical and hereditary alterations. Host-specific mycotoxins such as AK-toxin, AF-toxin, and AC-toxin have the obliterating impact on plants which causes DNA breakage, cytotoxic, apoptotic cell passing, hindering plant physiology by mitochondrial oxidative phosphorylation and influence layer penetrability. This article will explain an understanding of the illness instrument caused by a few Alter aria HSTs on have plants additionally the pathways of the poisons and how they caused illness in plants. These toxins have different negative impacts on cell organelles counting chloroplast, mitochondria, plasma film, core, Golgi bodies, etc.