The bistable network model of brain ischemia

Author(s): Konstantin-A. Hossmann

In a set of four interconnected papers DeGracia presents a novel network-based explanatory framework for conceptualizing the outcome of ischemic injury that deviates sharply from the currently prevailing approach of linear injury superposition. The thorough analysis of the increasing use of network theory in modern biology pro-vides the background for envisioning a new chapter of brain ischemia research which may be able to overcome the present dilemma of stroke treatment.