Association of sarcoidosis and psoriasis: a difficult diagnosis

Author(s): Houda Sahraoui, Saadia Ait Malek, Anass Kherrab, Miriem Ghazi, Abderrahim Elktaibi, Issam Rharrassi, Imane Elbouchti & Radouane Niamane

Sarcoidosis is a chronic multisystem disorder characterized by the formation of non caseating epithelioid cell granulomas affecting multiple organ systems. The role of the type 1 helper T (TH1) cells and type 17 helper T (TH17) cells in sarcoidal granuloma formation has been well documented. Moreover, TH17 and TH1 cells are also known to be involved in the pathogenesis of psoriasis. Thus, the concomitance of sarcoidosis and psoriasis is plausible based on these shared underlying immunological pathways. We report a case of a 46-years-old female with concomitant sarcoidosis and psoriasis, who has been misdiagnosed with psoriatic arthritis for a long time.

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