Abstract
Angiogenesis: Mechanisms, Roles, and Implications in Health and Disease
Author(s): Radhika SharmaAngiogenesis, the process by which new blood vessels form from pre-existing vessels, is a critical biological event that supports tissue growth, wound healing, and the response to hypoxia. This complex process involves a variety of cellular and molecular mechanisms, including endothelial cell proliferation, migration, and vessel maturation. Angiogenesis is tightly regulated, and its dysregulation can lead to pathological conditions, such as cancer, cardiovascular diseases, and diabetic retinopathy. This article explores the mechanisms of angiogenesis, its role in normal physiology, and the implications of abnormal angiogenesis in various diseases. Additionally, it discusses potential therapeutic strategies targeting angiogenesis for both disease treatment and tissue regeneration. Understanding angiogenesis offers critical insights into disease pathology and provides opportunities for the development of novel therapeutic approaches.