A Note on the Effective Production of Bioactive Molecules by an Edible Mushroom in a Batch Stirred Tank Bioreactor

Author(s): Nikolas Fokialakis

Production of bioactive metabolites of the common edible mushroom oyster mushroom. The biomass of the mushroom strain was made by submerged fermentation in a very batch stirred tank bioreactor and extracted by solvents of accelerating polarity. The chloride
and methyl alcohol extract were fractioned by totally different techniques together with sorption natural process and quick Centrifugal Partition natural process (FCPC). The structures of pure compounds were elucidated with 1D/2D NMR-spectroscopic analyses,
and chemical correlations combined with GC/MS and LC/MS experiments. Nineteen metabolites (e.g., fatty acids, phenolic resin metabolites, nucleotides and alkaloids) were isolated. on the far side the assembly of better-known metabolites, we tend to report
herein the assembly conjointly of trans-3, 4-dihydro-3, 4, 8-trihydroxynapthalen-1(2H) - one, indolo-3-carboxylic acid, 3-formylpyrrole and 4-hydroxybenzoic acid, that have pharmaceutical interest and area unit isolated for the primary time from genus Pleurotus