Positive Strand RNA Infection Peer-review Journals
The
replication of positive-strand RNA
viruses constitutes over one-third of all genera of viruses, and encompasses various constantly developing pathogens. Even the largest viral genomes encode merely hundreds of genes, while those of host
cells usually encode tens of thousands of genes, all
viruses are
gene poor as compared to their hosts. In contrast, positive-strand RNA
viruses target host factors to modulate the expression and defenses of the host genes. Host factors play an significant role in assembling the complex for viral RNA replication, selecting and recruiting templates for viral RNA replication, stimulating the RNA synthesis complex, and other measures. Either of these virus-host interactions may lead to host specificity, tissue specificity or
infection pathology.
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