ISSN: 2048-9145

Pharmaceutical Bioprocessing

Pharmacogenomics-journals

Pharmacogenomics is the study of the function of the genome in reacting to drugs. Its name reflects its mixture of pharmacology and genomics. Pharmacogenomics analyzes how the genetic structure of an organism affects its reaction to medications. It addresses the effect of the genetic variation acquired and inherited by correlating gene expression or single nucleotide polymorphisms with pharmacokinetics and pharmacodynamics on drug response in patients. The term pharmacogenomics is used interchangeably with pharmacogenetics, too. While both words relate to a genetically influenced drug reaction, pharmacogenetics focuses on single drug-gene interactions.  Pharmacogenomics aims to develop rational means for optimizing drug therapy with regard to the genotype of patients to ensure maximum efficacy with minimal adverse effects. Through the use of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed the "one-dose-fits-all" approach.    

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