Advanced Materials Science Research

Ogilvie’s Syndrome

 Ogilvie syndrome is that the acute dilatation of the colon within the absence of any mechanical obstruction in severely sick patients. Acute colonic pseudo-obstruction is characterised by large dilatation of the cavity (diameter > ten cm) and right colon on abdominal X-ray. it's a kind of colon, generally brought up as "acute colon," to tell apart it from harmful colon. The condition carries the name of the British doc Sir William Heneage Ogilvie (1887–1971), WHO 1st reported it in 1948. Ogilvie syndrome could occur once surgery, particularly following arteria bypass surgery and total joint replacement. Medicine that disturb colonic motility (e.g., anticholinergics or opioid analgesics) contribute to the event of this condition. The precise mechanism isn't best-known. The probable clarification is imbalance within the regulation of colonic motor activity by the involuntary systema nervosum. it's been postulated that reactivation of chickenpox herpes zoster virus (which causes pox and shingles) within the enteric ganglia could also be a explanation for Ogilvie syndrome. Acute colon develops attributable to abnormal enteric motility.    

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