Journal of Biochemistry Research

Microbial Metagenomics Impact Factor

Metagenomics facilitates the study of the diverse components of the human microbiome to determine the effect of numerous interactions between host and microbe and microbe. Metagenomics is a molecular tool used to analyze DNA acquired from environmental samples to study the microorganism community without the need to obtain pure crops. Functional metagenomics allows the high-resolution genomic study of unculturable bacteria and the identification of genomes with different environmental functions. In a genomic analysis metagenomics represents a new approach. This method makes access to the potential reservoir of novel soil genes. To reach this pool, DNA is isolated from an environmental sample, cloned to a appropriate vector, and converted into competent E. coli. The subsequent transformants are tested for novel biochemical, metabolic, and genetic characteristics in the metagenomic libraries. Metagenomics can also help in understanding competition and communication between microbials. This research may have far-reaching applications to all environments, whether they are within human digestive tract or in ocean vents. Functional metagenomics, such as antibiotics, can identify small molecules important for microbial survival. For antimicrobial activity metagenomic libraries can be assessed using functional assays to identify new antibiotics. Identifying new genes using metagenomics promises a great deal to understand the world around us and potentially to solve some of our health issues.

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