Marfan Syndrome Top Journals

 More than thirty totally different signs and symptoms area unit variably related to Marfan syndrome. the foremost outstanding of those have an effect on the skeletal, vas, and ocular systems, however all fibrous animal tissue throughout the body is affected. Most of the pronto visible signs area unit related to the systema skeletale. several people with Marfan syndrome grow to above-average height, and a few have disproportionately long, slender limbs with skinny, weak wrists and long fingers and toes. Besides moving height and limb proportions, individuals with Marfan syndrome might have abnormal lateral curvature of the spine (scoliosis), pectoral spinal curvature, abnormal indentation (pectus excavatum) or protrusion (pectus carinatum) of the bone, abnormal joint flexibility, a high-arched surface with jam-pawncked teeth Associate in Nursingd an malocclusion, flat feet, hammer toes, unerect shoulders, and unexplained stretch marks on the skin. It may cause pain within the joints, bones, and muscles. Some individuals with Marfan have speech disorders ensuing from symptomatic high palates and little jaws. Early arthritis might occur. alternative signs embody restricted vary of motion within the hips thanks to the leg bone head sticking out into abnormally deep hip sockets. the foremost serious signs and symptoms related to Marfan syndrome involve the vas system: undue fatigue, shortness of breath, heart palpitations, athletics heartbeats, or hurting diverging to the rear, shoulder, or arm. Cold arms, hands, and feet may be joined to MFS as a result of inadequate circulation. A murmur, abnormal reading on Associate in Nursing ECG, or symptoms of angina will indicate more investigation. The signs of regurgitation from prolapse of the mitral or arteria valves (which management the flow of blood through the heart) result from cystic medial degeneration of the valves, that is usually related to MFS  

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