Journal of Leukaemia & Lymphoma Research

Human Genetics Review Articles

 Human genetics is the study of the human genome and how genes are passed from generation to generation. The human genome is made up of 23 pairs of chromosomes (22 pairs of homologous chromosomes and one pair of sex chromosomes), each containing genes that code for proteins in the cell. In all pairs of homologous chromosomes, there are two forms of the same gene called alleles, which are passed from parent to child. Hereditary diseases are also transmitted from parents to offspring through different modes of transmission, such as dominant autosomics, X-linked and mitochondrial autosomics. These diseases often result from alterations in an individual's genes called mutations. While some mutations are mild, many cause cell dysfunction that manifests as disease. Understanding the mechanisms underlying the transmission of genetic material is essential for understanding and treating diseases that have a genetic component.  

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