Diabetes, Metabolic,therapeutic Efforts, Hypoglycemia, Hypoglycemic,heart Arrhythmic,symptomatic,causes,Type 2 Diabetes

The aim of managing diabetes is to establish an sufficient metabolic function to avoid or postpone problems from emerging. However, in many cases therapeutic efforts to keep the glycated hemoglobin values within the recommended target lead to an increased risk of hypoglycemia. Hypoglycemic events, particularly the extreme ones, are responsible for a major health , social and economic effect. At a health point of view, the physical morbidity of an incident of hypoglycemia varies at mild signs to paralysis and coma; it only induces abrupt, possibly heart arrhythmic mortality or brain damage because it is severe and sustained. Severe hypoglycemia is correlated with an elevated likelihood of coronary failure and dementia, as reported by a new meta-analysis.. Not only is severe hypoglycemia but also mild symptomatic hypoglycemia associated with increased risk of cardiovascular events, hospitalization of all causes and mortality of all causes. At a psychological point of view, numerous reports have explored the effect of hypoglycemia on quality of living, indicating a detrimental influence on emotional well-being and perceived self-perception of general health status.Hypoglycemia can interfere with many daily activities, such as driving, work performance and recreational activities. Furthermore, fear of hypoglycemia prevails over fear of long-term complications and is often responsible for poor adherence to therapy or improper compensation behaviours; the latter in turn is responsible for worse metabolic control of Maria Chiara Rossi, Incidence and Correlates of Type 2 Diabetes Hypoglycemia.

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