Chemical-pharmaceutical Analysis Open Access Journals
pharmaceutical
chemistry are disciplines of pharmacy at the intersection of chemistry, especially synthetic
chemistry , and
pharmacology and various other biological specialties, where they're involved design, chemical synthesis and development for market of pharmaceutical agents, or bio-active
molecules drugs. Compounds used as medicines are most frequently organic compounds, which are often divided into the broad classes of small organic
molecules are atorvastatin, fluticasone, clopidogrel and "biologics" infliximab, erythropoietin, insulin glargine, the latter of which are most frequently medicinal preparations of proteins natural and recombinant antibodies, hormones. Inorganic and organometallic compounds also are useful as
drugs like, lithium and platinum-based agents like Lithane and cisplatin also as gallium. In particular, medicinal
chemistry in its commonest practice—focusing on small organic molecules—encompasses synthetic
chemistry and aspects of natural products and computational
chemistry in close combination with chemical biology, enzymology and structural biology, together aiming at the invention and development of latest therapeutic agents. Practically speaking, it involves chemical aspects of identification, then systematic, thorough synthetic alteration of latest chemical entities to form them suitable for therapeutic use. It includes synthetic and computational aspects of the study of existing
drugs and agents in development in reference to their bioactivities biological activities and properties, i.e., understanding their structure-activity relationships (SAR). Pharmaceutical
chemistry is concentrated on quality aspects of medicines and aims to assure fitness for purpose of medicinal products.
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