Annals of Clinical Trials and Vaccines Research

Bone Marrow Open Access Journals

 Bone marrow is the soft spongy tissue. There are two types of bone marrow: red marrow that is responsible for producing red blood cells, white blood cells and platelets; and yellow marrow consisting mainly of fat cells. Bone homeostasis is regulated through osteoclasts, osteoblasts and osteocyte. Osteoblasts are differentiated from bone marrow mesenchymal stem cells and stimulate bone formation and calcification. Physiologic process is dexterously regulated through various physiological systems including hormones, cytokines and bone marrow environments. Bone marrow mesenchymal stem cells are multipotent stromal cells, which among other cell lineages that can differentiate into a variety of cell types including osteoblasts (bone cells), chondrocytes (cartilage cells), myoblasts (heart cells) and adipocytes (fat cells).  Differentiation of bone marrow mesenchymal stem cells may be involved in the development of osteoporosis.  

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