ISSN: 2048-9145

Pharmaceutical Bioprocessing

Biopharmaceutics Open Access

The study of the physical and chemical correctives of medicine and their proper dose as associated with the onset, duration, and intensity of drug action. Biopharmaceutics examines the interrelatedness of the physical/chemical properties of the drug, the dose kind (drug product) during which the drug is given, and also the route of administration on the speed and extent of general drug absorption. The importance of the drug substance and also the drug formulation on absorption, and in vivo distribution of the drug to the location of action, is represented as a sequence of events that precede stimulus of a drug’s therapeutic impact. First, the drug in its dose kind is taken by the patient by AN oral, blood vessel, hypodermic, transdermic, etc, route of administration. Next, the drug is free from the dose kind in a very predictable and characterizable manner. Then, some fraction of the drug is absorbed from the location of administration into either the encompassing tissue for native action or into the body (as with oral dose forms), or both. Finally, the drug reaches the location of action. A pharmacodynamic response results once the drug concentration at the location of action reaches or exceeds the minimum effective concentration (MEC). The urged dosing regimen, together with beginning dose, maintenance dose, dose kind, and dosing interval, is decided in concentration and weight.     

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