Journal of Biochemistry Research

Amino-acid-metabolism

            Amino acid metabolism is an important process that occurs in the human body to support many biological reactions. This article discusses the role of glutamate, transamination reactions, and various types of amino acids such as glycogenic, ketogenic, and mixed amino acids. Urea is the final product of protein metabolism (amino acid metabolism). Nitrogen from amino acids that are converted to ammonia is toxic to the body. This is converted to urea and is detoxified. Thus, urea forms 80-90% nitrogen which is excreted in the urine. The hereditary defect in amino acid metabolism is a family of genetic conditions where enzyme deficiency leads to the accumulation of positive-ninhydrin amino acids or proximal metabolites. They are conceptually synonymous with disorders caused by enzymatic defects and leading to the accumulation of organic acids. The metabolism of amino acids produces and consumes hydrogen ions depending on the type of amino acid. Metabolism of neutral amino acids ultimately leads to the formation of urea and carbon dioxide. Amino acid metabolism (AA) plays an important role in the biosynthesis of metabolites involved in neuron transmission, and has long been thought to play a role in ASD.

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