Allergen Immunotherapy Scholarly Journal
Allergen
immunotherapy is that the repeated
administration of allergen extracts to allergic individuals so as to supply long-term relief of symptoms and improvement in
quality of life during subsequent natural allergen exposure. Allergen
immunotherapy is very effective in IgE-mediated disease in patients with a limited spectrum (1 or 2) of allergies. In patients who develop systemic anaphylactic reactions to wasp/bee stings,
immunotherapy could also be life-saving and features a major impact on quality of lifetime of venom-allergic subjects. Unlike anti-allergic drugs,
immunotherapy has been shown to switch the underlying explanation for the disease, with proved future benefits. Allergen
immunotherapy could also be combined with appropriate allergen avoidance strategies.
Immunotherapy isn't competitive with the traditional use of pharmacotherapy and will be administered within the context of general advice regarding overall disease management. Subcutaneous (injection)
immunotherapy using high dose standardized vaccines (in general, containing 5-20 mcg of the main allergen in monthly maintenance injections) are of proved value. in sight of the danger of occasional severe allergic side effects, subcutaneous
immunotherapy should only be administered by trained persons in specialist clinics and with immediate access to adrenaline and other resuscitative measures. All patients should be observed within the clinic for a minimum of half-hour following injections. The optimum duration is around 3-5 years. in sight of the remote risk of great side effects, the risk/benefit ratio should be carefully considered altogether cases. Sublingual
immunotherapy has emerged as an efficient and safer alternative to the subcutaneous route for both seasonal and perennial disease. Sublingual
immunotherapy has also been shown to possess long-term benefits has the large advantage of self-administration within the patient’s home.
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