Jin, L., Wang, Z. S., Cao, Y., Sun, R. Q., Zhou, H., & Cao, R. Y. (2021). Establishment and optimization of a high-throughput mimic perfusion model in ambr® 15. Biotechnology Letters, 43(2), 423-433. View at Publisher|View at Google Scholar|View at Indexing
Yu Hongfei, Jiang Jiao, Dong Qinan, Huang Rong, Shang Hua, Ye Dongqing, & Liu Yanlin. Research on the factors related to ethanol fermentation of Saccharomyces cerevisiae in microplate screening. Food and Fermentation Industry , 47 (20), 8-14. View at Publisher|View at Google Scholar|View at Indexing
Dolata, K. M., Montero, I. G., Miller, W., Sievers, S., Sura, T., Wolff, C., ... & Robinson, C. (2019). Far-reaching cellular consequences of tat deletion in Escherichia coli revealed by comprehensive proteome analyses. Microbiological research, 218, 97-107. View at Publisher|View at Google Scholar|View at Indexing
Zedler, J. A., Mullineaux, C. W., & Robinson, C. (2016). Efficient targeting of recombinant proteins to the thylakoid lumen in Chlamydomonas reinhardtii using a bacterial Tat signal peptide. Algal research, 19, 57-62. View at Publisher|View at Google Scholar|View at Indexing
Zedler, J. A. Z. (2016). Expanding the toolkit of the Chlamydomonas reinhardtii chloroplast for biotechnological applications (Doctoral dissertation, University of Kent,). View at Publisher|View at Google Scholar|View at Indexing
Kalkman, S., Arentshorst, M., Hoekman, J., Boon, W., Uijtendaal, E., van Thiel, G., & Moors, E. (2020). In-hospital production of medicines: preparing for disruption. Trends in biotechnology, 38(10), 1045-1047. View at Publisher|View at Google Scholar|View at Indexing
Desai, P. M., Liew, C. V., & Heng, P. W. S. (2016). Review of disintegrants and the disintegration phenomena. Journal of pharmaceutical sciences, 105(9), 2545-2555. View at Publisher|View at Google Scholar|View at Indexing
Hwang, I., Kang, C. Y., & Park, J. B. (2017). Advances in hot-melt extrusion technology toward pharmaceutical objectives. Journal of Pharmaceutical Investigation, 47(2), 123-132. View at Publisher|View at Google Scholar|View at Indexing
Alam, M. A., Shi, Z., Drennen III, J. K., & Anderson, C. A. (2017). In-line monitoring and optimization of powder flow in a simulated continuous process using transmission near infrared spectroscopy. International journal of pharmaceutics, 526(1-2), 199-208. View at Publisher|View at Google Scholar|View at Indexing
Desai, P. M., Hogan, R. C., Brancazio, D., Puri, V., Jensen, K. D., Chun, J. H., ... & Trout, B. L. (2017). Integrated hot-melt extrusion–injection molding continuous tablet manufacturing platform: Effects of critical process parameters and formulation attributes on product robustness and dimensional stability. International journal of pharmaceutics, 531(1), 332-342. View at Publisher|View at Google Scholar|View at Indexing
Kim, S. H., Hwang, K. M., Cho, C. H., Nguyen, T. T., Seok, S. H., Hwang, K. M., ... & Park, E. S. (2017). Application of continuous twin screw granulation for the metformin hydrochloride extended release formulation. International journal of pharmaceutics, 529(1-2), 410-422. View at Publisher|View at Google Scholar|View at Indexing
Desai, P. M., Puri, V., Brancazio, D., Halkude, B. S., Hartman, J. E., Wahane, A. V., ... & Trout, B. L. (2018). Tablet coating by injection molding technology–Optimization of coating formulation attributes and coating process parameters. European Journal of Pharmaceutics and Biopharmaceutics, 122, 25-36. View at Publisher|View at Google Scholar|View at Indexing
Yeap, E. W., Acevedo, A. J., & Khan, S. A. (2019). Microfluidic extractive crystallization for spherical drug/drug-excipient microparticle production. Organic Process Research & Development, 23(3), 375-381. View at Publisher|View at Google Scholar|View at Indexing
Yeap, E. W., Acevedo, A. J., & Khan, S. A. (2019). Microfluidic extractive crystallization for spherical drug/drug-excipient microparticle production. Organic Process Research & Development, 23(3), 375-381. View at Publisher|View at Google Scholar|View at Indexing
Desai, P. M., Anbalagan, P., Koh, C. J., Heng, P. W., & Liew, C. V. (2018). Evaluation of tablet punch configuration on mitigating capping by a quality by design approach. Drug delivery and translational research, 8(6), 1635-1643. View at Publisher|View at Google Scholar|View at Indexing
Fischer, S., Handrick, R., & Otte, K. (2015). The art of CHO cell engineering: A comprehensive retrospect and future perspectives. Biotechnology advances, 33(8), 1878-1896. View at Publisher|View at Google Scholar|View at Indexing
Fischer, S., Mathias, S., Schaz, S., Emmerling, V. V., Buck, T., Kleemann, M., ... & Otte, K. (2015). Enhanced protein production by microRNA-30 family in CHO cells is mediated by the modulation of the ubiquitin pathway. Journal of biotechnology, 212, 32-43. View at Publisher|View at Google Scholar|View at Indexing
Fischer, S., Marquart, K. F., Pieper, L. A., Fieder, J., Gamer, M., Gorr, I., ... & Bradl, H. (2017). miRNA engineering of CHO cells facilitates production of difficult?to?express proteins and increases success in cell line development. Biotechnology and bioengineering, 114(7), 1495-1510. View at Publisher|View at Google Scholar|View at Indexing
Stiefel, F., Fischer, S., Sczyrba, A., Otte, K., & Hesse, F. (2016). miRNA profiling of high, low and non-producing CHO cells during biphasic fed-batch cultivation reveals process relevant targets for host cell engineering. Journal of biotechnology, 225, 31-43. View at Publisher|View at Google Scholar|View at Indexing
Schoellhorn, M., Fischer, S., Wagner, A., Handrick, R., & Otte, K. (2017). miR?143 targets MAPK7 in CHO cells and induces a hyperproductive phenotype to enhance production of difficult?to?express proteins. Biotechnology progress, 33(4), 1046-1058. View at Publisher|View at Google Scholar|View at Indexing
Inwood, S., Betenbaugh, M. J., & Shiloach, J. (2018). Methods for using small non-coding RNAs to improve recombinant protein expression in mammalian cells. Genes, 9(1), 25. View at Publisher|View at Google Scholar|View at Indexing
Weis, B. L., Guth, N., Fischer, S., Wissing, S., Fradin, S., Holzmann, K. H., ... & Otte, K. (2018). Stable miRNA overexpression in human CAP cells: Engineering alternative production systems for advanced manufacturing of biologics using miR?136 and miR?3074. Biotechnology and bioengineering, 115(8), 2027-2038. View at Publisher|View at Google Scholar|View at Indexing
Meyer, H. J., Reilly, D., Martin, S. E., & Wong, A. W. (2017). Identification of a novel miRNA that increases transient protein expression in combination with valproic acid. Biotechnology progress, 33(4), 1139-1145. View at Publisher|View at Google Scholar|View at Indexing
Wang, T. Y., & Guo, X. (2020). Expression vector cassette engineering for recombinant therapeutic production in mammalian cell systems. Applied microbiology and biotechnology, 104(13), 5673-5688. View at Publisher|View at Google Scholar|View at Indexing
Eitoku, M., Kato, H., Suganuma, N., & Kiyosawa, H. (2018). Markers associated with neuron-specific Ube3a imprinting during neuronal differentiation of mouse embryonic stem cells. Cytotechnology, 70(1), 45-53. View at Publisher|View at Google Scholar|View at Indexing
Janakiraman, V., Kwiatkowski, C., Kshirsagar, R., Ryll, T., & Huang, Y. M. (2015). Application of high?throughput mini?bioreactor system for systematic scale?down modeling, process characterization, and control strategy development. Biotechnology progress, 31(6), 1623-1632. View at Publisher|View at Google Scholar|View at Indexing
Tai, M., Ly, A., Leung, I., & Nayar, G. (2015). Efficient high?throughput biological process characterization: Definitive screening design with the Ambr250 bioreactor system. Biotechnology progress, 31(5), 1388-1395. View at Publisher|View at Google Scholar|View at Indexing
Xu, P., Clark, C., Ryder, T., Sparks, C., Zhou, J., Wang, M., ... & Scott, C. (2017). Characterization of TAP Ambr 250 disposable bioreactors, as a reliable scale?down model for biologics process development. Biotechnology progress, 33(2), 478-489. View at Publisher|View at Google Scholar|View at Indexing
Flitsch, D., Krabbe, S., Ladner, T., Beckers, M., Schilling, J., Mahr, S., ... & Büchs, J. (2016). Respiration activity monitoring system for any individual well of a 48-well microtiter plate. Journal of biological engineering, 10(1), 1-14. View at Publisher|View at Google Scholar|View at Indexing
Sandner, V., Pybus, L. P., McCreath, G., & Glassey, J. (2019). Scale?down model development in Ambr systems: An industrial perspective. Biotechnology journal, 14(4), 1700766. View at Publisher|View at Google Scholar|View at Indexing
Ladner, T., Flitsch, D., Schlepütz, T., & Büchs, J. (2015). Online monitoring of dissolved oxygen tension in microtiter plates based on infrared fluorescent oxygen-sensitive nanoparticles. Microbial cell factories, 14(1), 1-14. View at Publisher|View at Google Scholar|View at Indexing
Pollard, J., McDonald, P., & Hesslein, A. (2016). Lessons learned in building high?throughput process development capabilities. Engineering in Life Sciences, 16(2), 93-98. View at Publisher|View at Google Scholar|View at Indexing
Petroff, M. G., Feliciano, J., Pollard, D. J., Li, H., Linden, T. O., & Pollard, J. M. (2016). High?throughput purification tools for rapid upstream process development are interchangeable for biologics. Engineering in Life Sciences, 16(2), 114-123. View at Publisher|View at Google Scholar|View at Indexing
Rotondi, M., Grace, N., Betts, J., Bargh, N., Costariol, E., Zoro, B., ... & Rafiq, Q. A. (2021). Design and development of a new ambr250® bioreactor vessel for improved cell and gene therapy applications. Biotechnology Letters, 43(5), 1103-1116. View at Publisher|View at Google Scholar|View at Indexing
Terán, W. G. M., Aiello, R. C., & Bastidas, P. A. B. (2017). Control y automatización de un secador experimental de granos en lecho fluidizado pulsante. Revista Ciências Exatas, 23(1). View at Publisher|View at Google Scholar|View at Indexing
Betts, M. R. N. G. J., Costariol, N. B. E., Alvin, B. Z. C. J. H., & Rafiq, W. N. Q. A. (2021). Design and development of a new ambr250Ò bioreactor vessel for improved cell and gene therapy applications. View at Publisher|View at Google Scholar|View at Indexing
Fernandes, C. F., Pereira, S. S., Luiz, M. B., Silva, N. K., da Silva, M. C., Marinho, A. C. M., ... & Stabeli, R. G. (2021). Engineering of single-domain antibodies for next generation snakebite antivenoms. International journal of biological macromolecules. View at Publisher|View at Google Scholar|View at Indexing
Ling, W. L. W. (2019). Current Considerations and Future Advances in Chemically Defined Medium Development for the Production of Protein Therapeutics in CHO Cells. Cell Culture Engineering: Recombinant Protein Production, 279-294. View at Publisher|View at Google Scholar|View at Indexing
Sheen, D. A., Shen, V. K., Brinson, R. G., Arbogast, L. W., Marino, J. P., & Delaglio, F. (2020). Chemometric outlier classification of 2D-NMR spectra to enable higher order structure characterization of protein therapeutics. Chemometrics and Intelligent Laboratory Systems, 199, 103973. View at Publisher|View at Google Scholar|View at Indexing
Carrara, S. C., Ulitzka, M., Grzeschik, J., Kornmann, H., Hock, B., & Kolmar, H. (2021). From cell line development to the formulated drug product: The art of manufacturing therapeutic monoclonal antibodies. International Journal of Pharmaceutics, 594, 120164. View at Publisher|View at Google Scholar|View at Indexing
Jordan, M., Mac Kinnon, N., Monchois, V., Stettler, M., & Broly, H. (2018). Intensification of large-scale cell culture processes. Current opinion in chemical engineering, 22, 253-257. View at Publisher|View at Google Scholar|View at Indexing
Yongky, A., Xu, J., Tian, J., Oliveira, C., Zhao, J., McFarland, K., ... & Li, Z. J. (2019, November). Process intensification in fed-batch production bioreactors using non-perfusion seed cultures. In MAbs (Vol. 11, No. 8, pp. 1502-1514). Taylor & Francis. View at Publisher|View at Google Scholar|View at Indexing
Liu, T., Guo, H., Zhu, L., Zheng, Y., Xu, J., Guo, Q., ... & Wang, H. (2016). Fast characterization of Fc-containing proteins by middle-down mass spectrometry following IdeS digestion. Chromatographia, 79(21), 1491-1505. View at Publisher|View at Google Scholar|View at Indexing
