Abstract

Safety and efficacy of medications in researches

Author(s): Tagreed Altaei

Various websites have allowed the general population to read research articles on different subjects of treatment including osteoarthritis and osteoporosis, and other chronic diseases or syndrome. When people read that a drug is safe for the treatment of that disease, they will look for a way to use it without a prescription and without the supervision of specialist. Many drugs may be dispensed without a prescription in some countries, especially developing countries. Adverse effects of a substance may be undetectable in the exposure that fall within the therapeutic range in safety studies designed appropriately, observations and measurements used to detect toxicity in conventional animal toxicity studies, may not be evidence for human. Efficacy and safety need to be assessed in terms of categorical ratings or numerical scores, the criteria used for point assignment should be provided (e.g., definitions of point scores).