Pharmaceutical Formulation Based on Disintegrate Particle BreakdownAuthor(s): Chris Jordan
The breakdown of tiny molecules into fragments is a regular step in the drug design process. There are numerous strategies and techniques for dissolving molecules into smaller pieces. In this work, we introduce a novel straightforward method for the decomposition of molecules called MedChemFrag. This method enables the decomposition of molecules into non-overlapping pieces and is significant in terms of medicinal chemistry. It tries to disassemble drug-like compounds into a collection of rings and linkers that are similar to what medical chemists refer to as “fragments.” Our technique seeks to maintain the functional groups, which may reveal the specific interaction pattern, such as the amide groups, in contrast to most other attempts that sought to break molecules using retrosynthetic viable rules .