Abstract

Osteoarthritis: Emerging Therapies and Interventions for Disease Modification

Author(s): Ethan White*

Osteoarthritis (OA) is the most common form of arthritis, affecting millions of people worldwide, and is a leading cause of disability, particularly in older adults. Traditionally, OA management has focused on symptom relief through non-pharmacological interventions, such as exercise, weight management, and pharmacological treatments like nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. However, these therapies primarily address symptoms without modifying the underlying disease process. In recent years, a growing body of research has focused on identifying treatments that can slow, stop, or even reverse disease progression. This article reviews the emerging therapies and interventions for disease modification in OA, including biologics, stem cell therapy, platelet-rich plasma (PRP) injections, and novel pharmacologic agents. Additionally, the role of non-pharmacological strategies, such as exercise and joint protection, is discussed. Although some of these therapies have shown promising results, further research is needed to determine their long-term effectiveness and safety.