Choroidal Vascularity Index Changes in Children with FMF

Author(s): Sezer Taha, Teberik Kuddusi

Purpose: To evaluate choroidal thickness (CT) and choroidal vascularity index (CVI) changes in children with familial Mediterranean fever (FMF).

Methods: This retrospective study evaluated the CT and CVI values of 46 children with FMF patients according to their clinical and genetic data and in comparison with 46 controls. All eye examinations and EDI-OCT imaging were included in the analysis. The genetic subtypes of the FMF patients were determined. The acute phase reactants (fibrinogen, ESR, CRP) were examined.

Results: The mean CVI was 73.5% ± 4.8% in the FMF group and 74.7% ± 5.2% in the control group (p>0.05). CT and CVI were not significantly correlated with the genetic subtype in the FMF group (p>0.05).

Conclusion: There was no statistically significant difference in CVI and CT between pediatric FMF patients in remission and the control group. CVI and CT showed no correlation with FMF genetic subtype or acute phase reactants in FMF patients.