Abstract

Ankylosing Spondylitis and Systemic Lupus Erythematosus: A Rare Coexistence

Author(s): Xaria Cobin

Ankylosing spondylitis (AS) and systemic lupus erythematosus (SLE) are distinct autoimmune diseases, each with its own set of clinical and immunological characteristics. The coexistence of these two conditions within the same individual is exceedingly rare and presents unique challenges in diagnosis, management, and understanding the underlying pathogenic mechanisms. This case report explores the clinical presentation, diagnostic considerations, and treatment strategies for a patient with concurrent AS and SLE. We discuss the potential immunological and genetic factors contributing to this uncommon comorbidity and emphasize the importance of multidisciplinary care in optimizing the patient's quality of life. This case sheds light on the complex interplay between different autoimmune disorders and underscores the need for further research to elucidate the mechanisms underlying their coexistence.