Aneurysmal coronary artery disease: A focus on percutaneous treatment modalities

Author(s): Fauzia Vendrametto, Alessandro Pierri, Enrico Fabris, Davide Barbisan, Luca Restivo, Daniela Pavan, Gianfranco Sinagra

Aneurysmal Coronary Artery Disease (CAD) is an unsatisfactorily elucidated, multifaceted entity characterized by an abnormal enlargement of epicardial vessels. Unlike atherosclerotic coronary artery disease, the existing data regarding the optimal management and treatment options of aneurysmal CAD is poor and fragmentary due to the absence of large-scale clinical studies and cardiovascular society guideline recommendations. This paper is intended to provide a concise overview of definition, epidemiology, etiopathogenesis and clinical manifestations of aneurysmal CAD, with a special focus on contemporary percutaneous treatment modalities. In parallel, we briefly discuss two intriguing cases characterized by the superimposition of steno-occlusive and aneurysmal lesions, reflecting the challenges connected with the management of this entity in the elective and the emergency clinical setting, respectively.