ISSN: 2044-9038 (Print) 2044-9046 (Electronic)

Clinical Practice

Systems-Biology

Systems biology has been responsible for some of the most important developments in the science of human health and environmental sustainability. It is a holistic approach to deciphering the complexity of biological systems that starts from the understanding that the networks that form the whole of living organisms are more than the sum of their parts. It is collaborative, integrating many scientific disciplines – biology, computer science, engineering, bioinformatics, physics and others – to predict how these systems change over time and under varying conditions, and to develop solutions to the world’s most pressing health and environmental issues. This ability to design predictive, multiscale models enables our scientists to discover new biomarkers for disease, stratify patients based on unique genetic profiles, and target drugs and other treatments. Systems biology, ultimately, creates the potential for entirely new kinds of exploration, and drives constant innovation in biology-based technology and computation. Because systems biology requires constant attention to a very complex, very human social experiment, ISB fosters the kind of financial, social and psychological environment in which the world’s best scientists, technologists, engineers and mathematicians can collaborate and do their best work. A fundamental tenet of systems biology is that solving challenging biological problems always requires the development of new technologies in order to explore new dimensions of data space. New data types require novel analytical tools.    

High Impact List of Articles

Relevant Topics in Clinical