ISSN: 2044-9038 (Print) 2044-9046 (Electronic)

Clinical Practice

Stem Cells Review Articles

Although stem cell technology is just emerging, the regeneration of body parts is hardly a new concept. The regenerative capability of a living creature was recorded as early as 330 BC, when Aristotle observed that a lizard could grow back the lost tip of its tail. Since then, there have been slow but steady attempts at understanding the regenerative capabilities of human being and it is only in the last decade that we have seen an information explosion in the area of stem cell research. Stem cells are likely to revolutionize the entire health care delivery. The time is certainly ripe for all of us to familiarize ourselves. Stem cells derived from either peripheral blood, cord blood, bone marrow, or any adult tissue transported in the right medium to the laboratory is centrifuged, trypsinized, and propagated under ideal conditions and stored in the master cell bank (MCB). The MCB is further passaged to yield colonies of stem cells, given the right inductive signals using appropriate growth factors to allow them to differentiate into required cell types. These are injected or implanted into a patient as cell-based therapy. Homing will ensure that the stem cells reach the site of injury or tissues.    

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