Stem Cell Research and Regenerative Medicine

Spermatogonial Stem Cells Scholarly Peer-review Journal

 Spermatogonial stem cells (SSCs) are essential to sustaining spermatogenesis for a lifetime, and knowing how these cells perform has important implications for understanding infertility of male. A spermatogonial stem cell (SSC) is also known as type A spermatogonium not distinguished into a spermatocyte, a sperm cell precursor. Instead, they continue to divide into other spermatogonia, or stay dormant to maintain a spermatogonia reserve. On the other hand, type B spermatogonia differentiates into spermatocytes which in turn undergo meiosis in order to eventually form mature sperm cells. Several populations of cells that carry stem cell-like properties have recently been established in rodent seminiferous tubules, but it has been difficult to discern how these cells could drive spermatogenesis, and various models have been put forward to understand Spermatogonial stem cells dynamics.    

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