Journal of Leukaemia & Lymphoma Research

Sickle Cell Anemia Articles

 Sickle cell anemia (sickle cell disease) is a blood disorder caused by an inherited irregular hemoglobin (the protein that carries oxygen within the red blood cells). The abnormal hemoglobin causes red blood cells to look skewed (sickled under a microscope). Blood flow containing sickle cells to organs deprives damaged organs of blood and oxygen. Blood also has a chronically low oxygen level in sickle cell anaemia. This lack of oxygen-rich blood can damage and can be fatal to nerves and organs including your kidneys , liver and spleen. Conditions associated with low oxygen levels, elevated blood acidity or low blood volume may cause sickling. Common causes for the sickle cell crisis include: rapid temperature changes, which can widen the blood vessels. Very demanding or excessive exercise due to oxygen shortage. Bone marrow, or stem cell transplant, is the only proven treatment for sickle cell disease.  

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