ISSN: 2044-9038 (Print) 2044-9046 (Electronic)

Clinical Practice

Scholarly Journals In Germ Cell

Germ cells are the embryonic precursors of the gametes. They are set aside from the somatic cell lineages early in the development of most species. In the mouse. the germ cells, once they have formed, migrate through the tissues of the embryo to the gonad primordia (genital ridges), where they coassemble with somatic gonadal cells to form the sex cords. The sex cords are the forerunners of the seminiferous tubules of the male gonad or the ovarian follicles of the female gonad. They become sexually dimorphic as they form in the mouse embryo, between embryonic day 11.5 and E12.5. In addition to their complex differentiation into eggs and sperm, germ cells retain the property of pluripotency, which is required for the gametes to differentiate into new individuals. Germ cells that do not enter the gonad primordia can develop into germ line tumors later in life. Errors in germ cell differentiation can lead to infertility.  

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