Stem Cell Research and Regenerative Medicine

Resistant Hypertension Open Access

 Secondary hypertension (or, less commonly, inessential hypertension) may be a sort of hypertension which by definition is caused by an identifiable underlying primary cause. it's much less common than the opposite type, called hyperpiesia , affecting only 5-10% of hypertensive patients. it's many various causes including endocrine diseases, kidney diseases, and tumors. It can also be a side effect of the many medications. Other documented causes include diseases of the kidney. This includes diseases like polycystic renal disorder which may be a cystic genetic disease of the kidneys, PKD, which is characterized by the presence of multiple cysts (hence, "polycystic") in both kidneys, also can damage the liver, pancreas, and infrequently , the guts and brain. It are often autosomal dominant or autosomal recessive, with the autosomal dominant form being more common and characterized by progressive cyst development and bilaterally enlarged kidneys with multiple cysts, with concurrent development of hypertension, chronic renal disorder and kidney pain. Or chronic glomerulonephritis which may be a disease characterized by inflammation of the glomeruli, or small blood vessels within the kidneys. Hypertension also can be produced by diseases of the renal arteries supplying the kidney. this is often referred to as renovascular hypertension; it's thought that decreased perfusion of renal tissue thanks to stenosis of a main or branch arteria renalis activates the renin–angiotensin system. Also, some renal tumors can cause hypertension. The medical diagnosis of a renal tumor during a young patient with hypertension includes Juxtaglomerular cell tumor, Wilms' tumor , and renal cell carcinoma, all of which can produce renin.  

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