ISSN: 2041-6792

Clinical Investigation

Phytoecdysteroids

 Phytoecdysteroids are plant-derived ecdysteroids. Phytoecdysteroids are a category of chemicals that plants synthesize for defense against phytophagous (plant eating) insects. These compounds are mimics of hormones employed by arthropods within the molting process referred to as ecdysis. When insects eat the plants with these chemicals they'll prematurely molt, reduce , or suffer other metabolic damage and die. Chemically, phytoecdysteroids are classed as triterpenoids, the group of compounds that has triterpene saponins, phytosterols, and phytoecdysteroids. Plants, but not animals, synthesize phytoecdysteroids from mevalonic acid within the mevalonate pathway of the plant cell using acetyl-CoA as a precursor. Over 250 ecdysteroid analogs are identified thus far in plants, and it's been theorized that there are over 1,000 possible structures which could occur in nature.  more plants have the power to "turn on" the assembly of phytoecdysteroids when under stress, animal attack or other conditions.The term phytoecdysteroid also can apply to ecdysteroids found in fungi, albeit fungi aren't plants. The study of insect-plant interactions is currently one among the foremost actively investigated areas in chemical ecology, partly due to its interesting perspectives for the event of latest biopesticides with plant origins. These interactions involve numerous secondary plant metabolites which will interfere with behaviour, growth and/or development of insects. Phytoecdysteroids are secondary metabolites produced by many plants. They represent analogues of insect steroid hormones (ecdysteroids) that control insect growth, development, and reproduction.  

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