ISSN: 2044-9038 (Print) 2044-9046 (Electronic)

Clinical Practice

Online Genomics Information Journals

Genomics is a more recent term that describes the study of all of a person's genes (the genome), including interactions of those genes with each other and with the person's environment. Genomics includes the scientific study of complex diseases such as heart disease, asthma, diabetes, and cancer because these diseases are typically caused more by a combination of genetic and environmental factors than by individual genes. Genomics is offering new possibilities for therapies and treatments for some complex diseases, as well as new diagnostic methods. Genomics is helping researchers discover why some people get sick from certain infections, environmental factors, and behaviors, while others do not. For example, there are some people who exercise their whole lives, eat a healthy diet, have regular medical checkups, and die of a heart attack at age 40. There are also people who smoke, never exercise, eat unhealthy foods and live to be 100. Genomics may hold the key to understanding these differences. Apart from accidents (such as falls, motor vehicle accidents or poisoning), genomic factors play a role in nine of the ten leading causes of death in the United States (for example, heart disease, cancer and diabetes. See: Leading Causes of Death [cdc.gov]). All human beings are 99.9 percent identical in their genetic makeup. Differences in the remaining 0.1 percent hold important clues about the causes of diseases.     

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