ISSN: 2041-6792

Clinical Investigation

Next Generation Sequencing Seminars Innovations

 Next generation sequencing (NGS), deep sequencing or massively parallel are related terms that describe a DNA sequencing technology which has revolutionised genomic research. Entire human genetic data can be sequenced within a single day by using Next generation sequencing.   Next-generation sequencing (NGS) has revolutionized the biological sciences. With its ultra-high throughput, speed and scalability next generation sequencing allows researchers to perform a good sort of applications and to study biological systems at A level never before possible. The Advantages of Next-generation sequencing include Higher sensitivity to detect low-frequency variants and Faster turnaround time for high sample volumes and Comprehensive genomic coverage. To perform Sanger Sequencing, you add your primers to an answer containing the genetic information to be sequenced, and then divide up the answer into four PCR reactions. Each reaction contains a with dNTP mix with one among the four nucleotides substituted with a ddNTP (A, T, G, and C ddNTP groups). The rule behind the Next Generation Sequencing (NGS) is practically equivalent to thereto of Sanger sequencing, which depends on slim electrophoresis. The genomic strand is divided, and hence the bases in each part are distinguished by transmitted signs when the pieces are ligated against a format strand.  

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