Leydig Cell, Tumor,protein,treatment,cancer,publications,repression ,reduced ,weight
Leydig cell
tumor is a
model that is very analogous to human cachexia, since the
tumor caused gradual anorexia development as well as pronounced weight loss. TNF is developed by the Leydig cell tumors, and TNF causes cachexia. Hence, LPL activator NO-1886 administered to tumor-bearing rats in Leydig cell can have beneficial results. When Leydig
cells were inoculated into rats, the plasma total protein and albumin levels decreased early after inoculation, followed by a decrease in plasma glucose and HDL-C, with the animals showing signs of
malnutrition throughout. After
tumor inoculation, food consumption decreased, and subsequently the rats grew quickly leaner.Leydig cell inoculation has reduced the LPL activity in rat
adipose tissue and the weight of adipose tissue. NO-1886 avoided the reduction of carcass weight and starvation related to the repression of hunger attributed to Leydig cell tumours. From these results, the LPL activator is considered potentially beneficial in the treatment of
cancer cachexia and other wasting syndromes A journal is a periodic publication intended for further scientific progress, usually by reporting new research.While some of the oldest
journals publish
articles , reports, editorials, brief correspondence, documents, and research papers in a broad range of academic disciplines, most
journals are extremely focused.
Journals include publications checked by peer in an effort to guarantee the papers follow the consistency and academic integrity requirements of the publication. Every certain paper in a journal is part of the permanent science record.
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