Journal of Labor and Childbirth

Hyperglycemic Hormones Top Journal

 The hyperglycemic hormones are secreted during fasting to maintaining blood sugar levels and preventing hypoglycaemia. Hyperglycemia means high blood sugar or glucose. Blood glucose levels can vary from day to day. The amount of glucose in your blood is controlled by a hormone called insulin, which is secreted by pancreas. Insulin takes glucose out of blood and moves it into cells, where it is broken down to produce energy. Glucagon is a different peptide hormone secreted by pancreatic cells. Glucagon is secreted by pancreatic α-cells, and thought of because the body’s primary defence against low blood sugar levels. Glucagon induces hyperglycemia through stimulation of synthesis and mobilization of hepatic glucose, by activating glycogenolysis and gluconeogenesis and inhibition of glycolysis and glycogenesis. The degree of hyperglycemia can change overtime depending on metabolic cause. Temporary hyperglycemia is often benign and asymptomatic. During this period an abnormality in carbohydrate metabolism may occur which can be tested by measuring plasma glucose levels.To date, the primary hormonal disturbance in insulin-dependent diabetes remains defective insulin secretion.The hormones shows effect on both growth and metabolism. Growth wise, It increases amino acid uptake and involves in protein synthesis to form DNA and RNA formation. Metabolism wise, it increases the hepatic output of glucose, increases the secretion of insulin, but antagonize the effect of its receptor, so decreases glucose entrance to muscle.   

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