Genetic Drift Online Journals
Genetic drift (also known as allelic drift or the Sewall Wright effect) is the change in the frequency of an existing gene variant (allele) in a population due to random sampling of organisms. The alleles in the offspring are a sample of those in the parents, and chance has a role in determining whether a given individual survives and reproduces. A population's allele frequency is the fraction of the copies of one
gene that share a particular form. Genetic drift may cause
gene variants to disappear completely and thereby reduce genetic variation. It can also cause initially rare alleles to become much more frequent and even fixed.
When there are few copies of an allele, the effect of genetic drift is larger, and when there are many copies the effect is smaller. In the middle of 20th century, vigorous debates occurred over the relative importance of natural selection versus neutral processes, including genetic drift. Ronald Fisher, who explained natural selection using Mendelian genetics, held the view that genetic drift plays at the most a minor role in evolution, and this remained the dominant view for several decades. In 1968, population geneticist Motoo Kimura rekindled the debate with his neutral theory of molecular evolution, which claims that most instances where a genetic change spreads across a population (although not necessarily changes in phenotypes) are caused by genetic drift acting on neutral mutations
High Impact List of Articles
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Rupatadine for the treatment of allergic rhinitis and urticaria: a look at the clinical data
Erminia Ridolo, Marcello Montagni, Filippo Fassio, Ilaria Massaro, Oliviero Rossi, Cristoforo Incorvaia & Giorgio Walter Canonica
Review: Clinical Trail Outcomes: Clinical Investigation
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Rupatadine for the treatment of allergic rhinitis and urticaria: a look at the clinical data
Erminia Ridolo, Marcello Montagni, Filippo Fassio, Ilaria Massaro, Oliviero Rossi, Cristoforo Incorvaia & Giorgio Walter Canonica
Review: Clinical Trail Outcomes: Clinical Investigation
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Clinical trials in neglected tropical diseases: interview with Moses Bockarie
Moses Bockarie
Interview: Clinical Investigation
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Clinical trials in neglected tropical diseases: interview with Moses Bockarie
Moses Bockarie
Interview: Clinical Investigation
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Pharmacotherapy for adult acute lymphoblastic leukemia: an update from recent clinical trials and future directions
Brian L Burnette, Mrinal S Patnaik, Mark R Litzow
Review: Clinical Trail Outcomes: Clinical Investigation
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Pharmacotherapy for adult acute lymphoblastic leukemia: an update from recent clinical trials and future directions
Brian L Burnette, Mrinal S Patnaik, Mark R Litzow
Review: Clinical Trail Outcomes: Clinical Investigation
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Belimumab receives US FDA approval for treatment of systemic lupus
News and Views: Clinical Investigation
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Belimumab receives US FDA approval for treatment of systemic lupus
News and Views: Clinical Investigation
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Diagnosis and treatment of prostate cancer-related bone disease
Tilman Todenhoefer, Georgios Gakis, David Schilling, Gerhard Feil, Christian Schwentner,Arnulf Stenzl
Review Article: Clinical Investigation
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Diagnosis and treatment of prostate cancer-related bone disease
Tilman Todenhoefer, Georgios Gakis, David Schilling, Gerhard Feil, Christian Schwentner,Arnulf Stenzl
Review Article: Clinical Investigation
Relevant Topics in Clinical