Gabapentin

Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication used to treat partial seizures, neuropathic pain, hot flashes, and restless legs syndrome. It is Approve as one of a number of first-line medications for the surgery of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and middle neuropathic pain. About 15% of those given gabapentin for diabetic neuropathy or postherpetic neuralgia have a measurable benefit. Gabapentin is a taken by mouth. Common Side effect includes sleepiness and dizziness. Serious side effects include an increased risk of suicide, aggressive behavior, and drug reactions. It is unclear if it is safe during pregnancy or breastfeeding. Lower doses are recommended in those with kidney disease associated with a low kidney function. Gabapentin is a gabapentinoid. It has a molecular structure similar to that of the neurotransmitter γ-aminobutyric acid (GABA) and acts by inhibiting certain calcium channels. It was the eleventh most commonly prescribed medication in the United States, with more than 46 million prescriptions.

 

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