BioTechniques is an open access journal motivated to the publication of related technical tools, original laboratory methods and methods-oriented review articles that are of wide interest to professional life experts as well as to scientists from other fields (e.g., physics, chemistry, computer science) interested in life science applications of their technologies. BioTechniques has been the principal peer-reviewed journal for methods related research. Suitable manuscripts are then subject to fair, rigorous, and rapid peer review. BioTechniques is committed to serving the interests of both readers and authors. No submission, publication, or page fees are levied. The journal maintains its well established policy of accepting manuscripts on the basis of scientific grade alone. Reports explaining substantive modifications to existing methods, innovative new methods, and innovative applications of existing methods to scientific questions or new models are appropriate subjects for the journal.