ISSN: 2041-6792

Clinical Investigation

Biochips Top Review Journals

Biochips relate to variety of technologies that involve the merging of semiconductor and biological sciences. The most common form is predicated on an array of molecular sensors arranged on alittle surface _ typically mentioned as “lab-on-chip.” The underlying mechanism utilizes microfluidic micro-electromechanical systems (MEMS) technology. These devices are wont to analyze biological elements like DNA, RNA and proteins, additionally to certain chemicals. Biochip, a bio-microarray device, has been extensively studied and developed to enable large-scale genomic, proteomic and functional genomic analyses. A biochip composed chiefly three types: DNA microarray, protein microarray, and microfluidic chip. With the mixing of microarray and microfluidic systems, a micro total analysis system, which is usually called a lab-on-a-chip (LOC) system, is produced. Protein biochips/microarrays are well-established tools for research and a few products for in vitro diagnostics are available commercially. Advances of nanotechnology have continuously reduced the dimensions of the biochip which successively reduced the manufacturing cost and increased the high throughput capability. Based on the convenience of low expense, immense throughput and miniaturization, this technology has large capability to be an important and powerful appliances for clinical research, diagnostics, drug development, toxicology studies, and patient selection for clinical trials.      

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