Autoimmunity Journals

 Autoimmunity is that the system of immune responses of an organism against its own healthy cells and tissues. Any malady that results from such AN aberrant reaction is termed AN "autoimmune disease". outstanding examples embody disorder, post-infectious IBS, DM kind one, Henloch Scholein Pupura (HSP sarcoidosis, systemic lupus erythematosus (SLE), Sjögren syndrome, white blood cell granulomatosis with polyangiitis, Hashimoto's rubor, exophthalmos, disorder purpura, hypoadrenocorticism, arthritis (RA), Marie-Strumpell disease, myositis (PM), myositis (DM) and MS (MS). reaction diseases area unit fairly often treated with steroids.   While a high level of pathology is unhealthy, an occasional level of pathology may very well be helpful. Taking the expertise of a helpful consider pathology any, one would possibly hypothesis with intent to prove that pathology is often a protection mechanism of the vertebrate system to survive. The system doesn't haphazardly lose the power to differentiate between self and non-self, the attack on cells could also be the consequence of sport metabolic processes necessary to stay the blood chemistry in equilibrium. Second, pathology could have a job in permitting a fast reaction within the early stages of an infection once the provision of foreign antigens limits the response (i.e., once there are few pathogens present). In their study, Stefanova et al. (2002) injected AN anti-MHC category II protein into mice expressing one style of MHC category II molecule (H-2b) to quickly stop CD4+ T cell-MHC interaction.