ISSN: 2044-9038 (Print) 2044-9046 (Electronic)

Clinical Practice

Auto Inflammatory Diseases Journals

Auto inflammatory diseases area group of clinical conditions other than autoimmune diseases, characterized by recurrent inflammatory episodes. From apathogenetic point of view they are determined by a dys regulation of innate immunity, without involvement of specific immunity (auto reactive T cells and auto antibodies). Recently, the increased knowledge in the field of auto inflammation highlighted shared immune mechanisms in the pathogenesis of both classical monogenetic and multifactorial auto inflammatory diseases and a broad spectrum of chronic age-related inflammatory pathologies. The current increase in the prevalence of chronic inflammatory diseases makes this subject of topical interest. In the light of these considerations, we propose an update of auto inflammatory diseases and a new interpretation of auto inflammation with both theoretical and clinical implications. The term “auto inflammatory” appeared on Cell in the spring of 1999 to describe an emerging family of clinical disorders, different from autoimmune syndromes. These were in fact characterized by episodes of apparently unprovoked inflammation, due to dys regulation of the innate immune system, without auto reactive T lymphocytes and auto antibodies and therefore different from classical autoimmune diseases. OMICS International has focused on meeting the needs of the scientific community, through strong tie-up with business and industry, while at the same time accomplishing international benchmarks and accreditation standards.     

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