Acne Innovations
Acne is characterized by primary lesions on the face, chest, and back, and by a variety of other signs and symptoms. In particular, acne inflammatory lesions result from Propionibacterium acnes colonization and are of particular relevance as they will cause permanent scarring. Acne also causes significant psychological
morbidity in affected patients. Farmaka Acne Cream (FAC) may be a novel, film-forming cream developed to treat mild and moderate acne. In vitro studies have demonstrated that FAC is as effective as 5% peroxide in inhibiting growth of P. acnes. In 32 subjects with mild or moderate acne, FAC reduced all the main signs and symptoms of the disease. These included itching, erythema, and scaling, as well as reductions in the numbers of papules, pustules, and open and closed comedones.Most subjects (90%) reported tolerability nearly as good or excellent , while clinical efficacy and cosmetic acceptability were judged nearly as good . Using a solar stimulator, one minimal erythema dose was delivered to one side of the back from days 11 to 13. No cases of contact sensitization or photosensitization were observed, and FAC is taken into account safe to be used in intense sunlight. In vitro and in vivo studies provide evidence for the security and clinical benefits of FAC, a promising candidate for the treatment of mild and moderate acne
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