Synthetic Medicinal Chemistry: Advancing Drug Discovery and Development

Author(s): Dr. Hossein Sharifi

Synthetic medicinal chemistry plays a crucial role in the development of novel therapeutic agents to address unmet medical needs. This interdisciplinary field combines principles from organic chemistry, pharmacology, and molecular biology to design and synthesize new chemical entities with desired pharmacological properties. By utilizing synthetic approaches, researchers can optimize the drug-like characteristics of molecules, such as potency, selectivity, and bioavailability, to improve their therapeutic efficacy and minimize potential side effects. This abstract provides an overview of the principles and strategies involved in synthetic medicinal chemistry, highlighting the importance of structureactivity relationship studies, rational drug design, and the utilization of modern synthetic techniques. Moreover, it discusses the significance of computational methods and high-throughput screening in accelerating the discovery and optimization of new drug candidates. Overall, synthetic medicinal chemistry serves as a powerful tool in the pursuit of innovative therapeutic interventions, contributing to advancements in healthcare and the treatment of various diseases.