Abstract

Recurrent Cerebral Venous Sinus Thromboses (CVSTââ?¬â?¢s) and Livedo Reticularis Rash ââ?¬â?? A Case of Sneddon Syndrome

Author(s): V Shukla, VA Singh, N St Louis, L Akan, N Solomon, C Greene, VRS Singh, M Fernandes, N Hallai, P Maharaj4, K Khan-Kernahan5, S Devarashetty5, and E Persad5

Sneddon Syndrome (SS) is a rare, progressive small and medium-vessel vasculopathy characterized by livedo racemosa and ischaemic cerebrovascular events. An 18-year-old female of East Indian descent presented with recurrent Cerebral Venous Sinus Thromboses and a livedo reticularis rash. She was treated for a CNS vasculitis/Catastrophic Antiphospholipid Syndrome when she presented with refractory status epilepticus and raised intracranial pressure. Her neurological state gradually improved (coma ->vegetative state ->minimally conscious ->conscious). Skin biopsy was suggestive of an obstructive vasculopathy. There are few case reports describing SS. We aim to highlight the clinical course and treatment of this rare diagnostic entity.