Abstract

Mean platelet volume measurements affecting evaluation of parameters in dialysis patients (The affective of mean platelet volume)

Author(s): Nilgul Akalin, Mehmet Koroglu, Selcuk Sezikli, Senol Senturk and Murat Asik

Background: We aimed to show the levels of mean platelet volum and also; the existence of effects parameters was investigated on mean platelet volum levels; in patients with dialysis replasman treatment.
Materials: This study was included to the control group and patients with peritoneal dialysis and patients with hemodialysis treatments and their dialysis adequate were ensured. Venous blood samples were taken from all of the cases and mean platelet volum levels, platelet, hemoglobin, insulin resistance, C- peptide and biochemical parameters were measured.
Results: Ä°nsulin resistance and C-peptid levels were found higher in the control group than in the dialysis groups. Platelet levels were found significiantly higher in dialysis groups than the control group and platelet levels were determined to be higher in the peritoneal dialysis group than the patients with hemodialysis group. Mean platelet volum levels were found higher in the dialysis patient groups than the control group. No difference statistical was observed for the levels of mean platelet volum; between dialysis groups. The relationship between was not shown to the levels of mean platelet volum with other parameters; in patients with dialysis treatment. Positive correlation was found the between platelet counts with mean platelet volum; in the control group.
Conclusion: We thought that the precence of end stage renal disease and dialysis therapies might cause to increase of mean platelet volum levels; in dialysis patients. This condition can be explained by the increase of atherosclerotic complication risk and inflammation risk; in dialysis patients.