In Renal Diseases, the Role of Epigenetically Regulated InflammationAuthor(s): Sarah Collins
Renal disease research has made remarkable strides in recent decades. The role of inflammation in kidney disease has been highlighted by experimental evidence in this field. Cellular responses to intrinsic and extrinsic stimuli are altered as a result of immunometabolic reprogramming and epigenetic dynamics; These factors are current research hotspots because they determine cell identity and cell fate decisions. This survey centers around late discoveries and arising ideas in epigenetics and provocative guideline and their impact on renal illnesses. The purpose of this review is to provide new avenues for future research on inflammation-related renal disease and the development of drugs, as well as to summarize the roles and mechanisms of various epigenetic modifications in renal inflammation and injury.