Abstract

Autoimmunity: Mechanisms, Implications, and Advances in Treatment

Author(s): Sree Jhu

Autoimmunity refers to a condition where the body's immune system mistakenly attacks its own tissues and organs. This phenomenon occurs when the immune system fails to distinguish between self and non-self, leading to chronic inflammation and tissue damage. The causes of autoimmunity are multifactorial, involving genetic predisposition, environmental triggers, and immune system dysregulation. Autoimmune diseases, such as rheumatoid arthritis, lupus, and multiple sclerosis, are complex, often chronic conditions that can significantly impact an individual's quality of life. This article explores the underlying mechanisms of autoimmunity, the role of genetic and environmental factors, the impact of autoimmune diseases on patients, and recent advances in treatment options. Understanding the pathophysiology of autoimmunity is essential for developing targeted therapies and improving patient outcomes.


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